In a study published in Nature, researchers report the successful in vitro reconstitution of meiotic DNA double-strand breaks (DSBs) formation. Meiotic recombination generates genetic diversity and ...

DSBs are more likely to occur in some genomic regions than others. Elucidating mechanisms shaping the DSB “landscape” requires identifying the biochemical factors involved, understanding how they ...

Meiosis is a specialised form of cell division that produces haploid gametes from diploid progenitor cells, ensuring the maintenance of chromosome number across generations. Central to this process is ...

Meiotic recombination assures genetic variation during breeding. During meiotic prophase I, chromosomes are organized in a loop-base array by a proteinaceous structure called meiotic chromosome axis ...

One observation, made more than 80 years ago about precisely where on chromosomes crossovers happen, has fueled research in Dr. Gerry Smith’s laboratory in the Basic Sciences Division. That ...

The biological research of UC Santa Cruz’s Needhi Bhalla to determine the molecular motions at the heart of heredity has yielded a new discovery: The proper transfer of genetic materials depends on ...

During meiosis, paternal and maternal chromosomes duplicate, pair, and exchange parts of their DNA in a process called meiotic recombination. In order to mediate this exchange of genetic material, ...

Recombination between homologous chromosomes is essential for successful meiosis. It drives genetic diversity in germline cells and provides the necessary scaffolding for accurate, balanced ...

Genetic recombination (also known as genetic reshuffling) is the exchange of genetic material between different organisms which leads to production of offspring with combinations of traits that differ ...

A research team at the IPK Leibniz Institute has developed a method that enables the detailed observation of female ...