Danforth Center scientists Tessa Burch-Smith and Kirk Czymmek, in collaboration with researchers at the CryoEM Facility at Stanford University, are embarking on a pioneering initiative to develop new ...

Biochemist Wolfgang Baumeister, director emeritus of the Max Planck Institute of Biochemistry, has received the 2025 Shaw Prize in Life Science and Medicine. The Shaw Prizes have been awarded annually ...

Cryo-electron tomography (cryo-ET) can provide invaluable insights into subcellular structures in their native environment at molecular resolution. Cryo-focused ion beam (cryo-FIB) has been widely ...

Researchers have used cryo-electron tomography to uncover new details of the molecular structure of synaptic vesicles, which help transport neurotransmitters in the brain. The study could inform ...

Left side of figure shows the process of individual-particle cryo-electron tomography (IPET) where RNA samples are frozen on a grid, then imaged by tilting the sample at different angles. The images ...

Mitochondria are the powerhouses in our cells, producing the energy for all vital processes. Using cryo-electron tomography, researchers at the University of Basel, Switzerland, have now gained ...

Cryo-electron microscopy (cryo-EM) has revolutionalized our understanding of the intricate molecular machinery that governs life. It has elucidated the three-dimensional (3D) structure of biological ...

Researchers have discovered and characterized at the atomic level a mechanism that enables bacterial pathogens—including ...